Synthesis and biological activity of nitrogen-containing derivatives of estafiatin

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dc.contributor.author Merkhatuly, N.
dc.contributor.author Vojtíšek, P.
dc.contributor.author Abeuova, S.B.
dc.contributor.author Omarova, A.T.
dc.contributor.author Iskanderov, A.N.
dc.date.accessioned 2019-03-20T08:43:12Z
dc.date.available 2019-03-20T08:43:12Z
dc.date.issued 2014-06-30
dc.identifier.citation Synthesis and biological activity of nitrogen-containing derivatives of estafiatin / N.Merkhatuly [et al.] // Қарағанды универисетінің хабаршысы. ХИМИЯ Сериясы.=Вестник Карагандинского университета. Серия ХИМИЯ.=Bulletin of the Karaganda University. CHEMISTRY Series. – 2014. - № 2. - P.4-8. ru_RU
dc.identifier.issn 0142-0843
dc.identifier.uri http://rep.ksu.kz:80//handle/data/4498
dc.description.abstract The reactions of guaianolide of estafiatin with various amines were investigated. It was shown that the aminolysis reactions of γ-lactone ring of estafiatin or reactions of Michael-type conjugate addition or tandem conversions of Michael and Knoevenagel-type were carried out depending on the nature of amines. The regularity of proceeding of estafiatin reactions with secondary aliphatic and aliphatic-aromatic amines was detected. It lies in the fact that the reactions proceed exclusively by Michael reaction and they are completely regioand stereoselective. It was revealed that synthetic nitrogen-containing derivatives of estafiatin had antibacterial and antioxidant activity. ru_RU
dc.language.iso en ru_RU
dc.publisher KSU Publ. ru_RU
dc.relation.ispartofseries Қарағанды универисетінің хабаршысы. ХИМИЯ Сериясы.=Вестник Карагандинского университета. Серия ХИМИЯ.=Bulletin of the Karaganda University. CHEMISTRY Series.;№ 2(74)/ 2014
dc.subject guaianolide ru_RU
dc.subject estafiatin ru_RU
dc.subject aminolysis ru_RU
dc.subject aliphatic amines ru_RU
dc.subject Michael reaction ru_RU
dc.subject tandem reaction ru_RU
dc.subject antibacterial and antioxidant activity ru_RU
dc.title Synthesis and biological activity of nitrogen-containing derivatives of estafiatin ru_RU
dc.title.alternative Эстафиатиннің азотқұрамды туындыларының синтезі жəне биологиялық белсенділігі ru_RU
dc.title.alternative Синтез и биологическая активность азотсодержащих производных эстафиатина ru_RU
dc.type Article ru_RU
dcterms.type Article


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