Biologically active derivatives of fullerene C60. Current state and development prospects

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dc.contributor.author Fazylov, S.D.
dc.contributor.author Nurkenov, О.А.
dc.contributor.author Muldakhmetov, Z.M.
dc.contributor.author Gazaliev, A.M.
dc.contributor.author Аrinova, А.Е.
dc.contributor.author Ibraev, M.K.
dc.contributor.author Vlasova, L.M.
dc.contributor.author Fazylov, A.S.
dc.date.accessioned 2020-11-09T04:53:39Z
dc.date.available 2020-11-09T04:53:39Z
dc.date.issued 2020-09-30
dc.identifier.citation Fazylov S.D. Biologically active derivatives of fullerene C60. Current state and development prospects/S.D. Fazylov [et al]//Қарағанды университетінің хабаршысы. Химия сериясы = Вестник Карагандинского университета. Серия Химия.= Bulletin of the Karaganda university. CHEMISTRY Series. -2020. №3. Р.11-20. ru_RU
dc.identifier.uri http://rep.ksu.kz/xmlui/handle/data/10153
dc.description.abstract The article presents literature review on the physicochemical and biological properties of fullerene C60, as well as the authors' own experimental data on the synthesis of fullerene derivatives of amines and natural alkaloids. It is shown that the presence of a fullerene fragment in the structure of the compound provides a significant improvement or the appearance of qualitatively new mechanical, chemical, physical, biological and other properties associated with the manifestation of nanoscale factors. The issues of the relationship of the structure, water solubility and biological activity of fullerene С60 derivatives are considered. Many biologically active effects of various modified derivatives of fullerene C60 are described, which have membrane- active, antibacterial, antiviral, immunomodulating, HIV inhibitory enzymes and other properties. It was noted that preparations containing a fullerene fragment are effective against hepatitis C virus, and are also able to efficiently trap free radicals. Derivatives of fullerenes can also be used as antioxidant, neuroprotective and other agents. Particular attention is paid to the authors' own results on the synthesis of amino derivatives of fullerenes. ru_RU
dc.language.iso en ru_RU
dc.publisher KSU Publ. ru_RU
dc.relation.ispartofseries Қарағанды университетінің хабаршысы. Химия сериясы = Вестник Карагандинского университета. Серия Химия.= Bulletin of the Karaganda university. CHEMISTRY Series.;№3(99)/2020
dc.subject fullerene C60 ru_RU
dc.subject fulleropyrrolidines ru_RU
dc.subject nanoscale factors ru_RU
dc.subject amino fullerenes ru_RU
dc.subject Prato reaction ru_RU
dc.title Biologically active derivatives of fullerene C60. Current state and development prospects ru_RU
dc.title.alternative Фуллерен С60 биологиялық белсенді туындылары. Қазіргі заманғы жағдайы мен даму болашағы ru_RU
dc.title.alternative Биологически активные производные фуллерена С60. Современное состояние и перспективы развития ru_RU
dc.type Article ru_RU


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